ParkinsonFranceV1, Main, Exploration, bibRecord, 000B28

CIRCADIAN INSIGHTS INTO DOPAMINE MECHANISMS

Identifieur interne : 000B28 ( Main/Exploration ); précédent : 000B27; suivant : 000B29

CIRCADIAN INSIGHTS INTO DOPAMINE MECHANISMS

Auteurs : J. Mendoza [France] ; E. Challet [France]

Source :

Neuroscience [ 0306-4522 ] ; 2014.

RBID : Pascal:15-0041986

Descripteurs français

Pascal (Inist)
- Rythme circadien, Dopamine, Récompense, Métamfétamine, Alimentation, Comportement alimentaire.

English descriptors

KwdEn :
- Circadian rhythm, Dopamine, Feeding, Feeding behavior, Metamfetamine, Reward.

Abstract

Almost every physiological or behavioral process in mammals follows rhythmic patterns, which depend mainly on a master circadian clock located in the hypothalamic suprachiasmatic nucleus (SCN). The dopaminergic (DAergic) system in the brain is principally implicated in motor functions, motivation and drug intake. Interestingly, DA-related parameters and behaviors linked to the motivational and arousal states, show daily rhythms that could be regulated by the SCN or by extra-SCN circadian oscillator(s) modulating DAergic systems. Here we examine what is currently understood about the anatomical and functional central multi-oscillatory circadian system, highlighting how the main SCN clock communicates timing information with other brain clocks to regulate the DAergic system and conversely, how DAergic cues may have feedback effects on the SCN. These studies give new insights into the role of the brain circadian system in DA-related neurologic pathologies, such as Parkinson's disease, attention deficit/ hyperactive disorder and drug addiction.

Affiliations:

Links toward previous steps (curation, corpus...)

to stream PascalFrancis, to step Corpus: 000003
to stream PascalFrancis, to step Corpus: 000012
to stream PascalFrancis, to step Curation: 001275
to stream PascalFrancis, to step Checkpoint: 000046
to stream Main, to step Merge: 000B41
to stream Main, to step Curation: 000B28

Le document en format XML

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<front><div type="abstract" xml:lang="en">Almost every physiological or behavioral process in mammals follows rhythmic patterns, which depend mainly on a master circadian clock located in the hypothalamic suprachiasmatic nucleus (SCN). The dopaminergic (DAergic) system in the brain is principally implicated in motor functions, motivation and drug intake. Interestingly, DA-related parameters and behaviors linked to the motivational and arousal states, show daily rhythms that could be regulated by the SCN or by extra-SCN circadian oscillator(s) modulating DAergic systems. Here we examine what is currently understood about the anatomical and functional central multi-oscillatory circadian system, highlighting how the main SCN clock communicates timing information with other brain clocks to regulate the DAergic system and conversely, how DAergic cues may have feedback effects on the SCN. These studies give new insights into the role of the brain circadian system in DA-related neurologic pathologies, such as Parkinson's disease, attention deficit/ hyperactive disorder and drug addiction.</div>
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{{Explor lien
   |wiki=    Wicri/Sante
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   |flux=    Main
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   |type=    RBID
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This area was generated with Dilib version V0.6.29.
Data generation: Wed May 17 19:46:39 2017. Site generation: Mon Mar 4 15:48:15 2024

	La maladie de Parkinson en France (serveur d'exploration)
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

La maladie de Parkinson en France (serveur d'exploration)

CIRCADIAN INSIGHTS INTO DOPAMINE MECHANISMS

CIRCADIAN INSIGHTS INTO DOPAMINE MECHANISMS

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri